I am on DAY 2 of KISQALI (Ribociclib! Yesterday I took my first three pills and this morning I took my second three pills. So far, no side effects, but it is early. I definately feel how the steroid is ramped up a bit as this drug increases the steroid amount in my system. That kept me up last night. But I am taking 1-2 naps during the day so all in all, I get about 6-7 hours per day/night. Once I feel better I will wean off the steroids entirely so that will help my system relax and hopefully restore my sleep. I do believe I am on the mend. I feel a bit better each week. These medications are a true modern miracle! KISQALI is a CDK4/6 inhibitor: It works by forcing cancer cells into a permanent sleep state known as cellular senescence. While these senescent cells cannot divide, they remain alive but in a dormant state. I am hoping the cancer is very sensitive to them and that I can stay on them for 5 years before having to switch medications to suppress their potential awakening. That would be a blessing. I think I through the worst of it and thank goodness because this has been painful and scary. I still have headaces and crazy rib pain from the lesions. My bones still feel super fragile like they could crack but they will repair in 12 months, thanks to ZOMETA injections. I will have my first injection in about 3 weeks, as long as I can handle the KISQUALI and show no adverse reactions. Thank you for following my blog and for being my friend while on this journey, either close or from afar.

Comments

  1. BethAugust 16, 2026 at 3:18 PM

    Thank your for sharing what is happening, and keeping us up to date on how you are doing. I'm happy to hear that you feel a bit better, and am keeping you in my prayers. Hope to see you soon.

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